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Gene Information
Gene symbol: CCR1
Gene name: chemokine (C-C motif) receptor 1
HGNC ID: 1602
Synonyms: CKR-1, MIP1aR, CD191
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
16365449
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U83A efficiently and potently induced calcium mobilization in cells expressing single human CCR1, CCR4, CCR6, or CCR8, with EC50 values <10 nM.
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2 |
16365449
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U83A-Npep acted only as antagonist, efficiently blocking binding of CCL3 to CCR1 or CCR5 on differentiated monocytic/macrophage leukemic cells.
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3 |
16365449
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Furthermore, CCL3 induction of calcium signaling via CCR1 and CCL1 induced chemotaxis via CCR8 in primary human leukocytes was inhibited.
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4 |
16365449
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However, late in infection, when full-length U83A is made, chemoattraction of CCR1-, CCR4-, CCR5-, CCR6-, and CCR8-bearing monocytic/macrophage, dendritic, and T lymphocyte cells can facilitate dissemination via lytic and latent infection of these cells.
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