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Gene Information

Gene symbol: CD244

Gene name: CD244 molecule, natural killer cell receptor 2B4

HGNC ID: 18171

Synonyms: 2B4, NAIL, NKR2B4, Nmrk, SLAMF4

Related Genes

# Gene Symbol Number of hits
1 CD8A 1 hits
2 NCR1 1 hits

Related Sentences

# PMID Sentence
1 16275895 Phorbol ester-stimulated CD8+ T cells also expressed CD244 and CD94, and CD4+ T cells expressed CD94.
2 21214542 Here, we show that upon in vitro exposure to influenza, NKp46 expression on NK cells decreases, whereas expression of 2B4, an activating receptor that can enhance natural cytotoxicity in synergy with NKp46, is up-regulated.
3 21214542 Altogether, our results further suggest that NKp46 may play an important role in the innate immune response to human influenza and reveal that exposure to influenza antigens is associated with a previously unrecognized increase in 2B4 expression that can impact NK cell activity against the virus.