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Gene Information
Gene symbol: CYBB
Gene name: cytochrome b-245, beta polypeptide
HGNC ID: 2578
Synonyms: GP91-PHOX, NOX2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NOX5 | 1 hits |
| 2 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17030496 | Both AM apoptosis and the number of macrophages containing apoptotic bodies are reduced in iNOS(-/-) as compared to control or gp91(phox-/-) mice. iNOS(-/-) mice recruit neutrophils and generate TNF-alpha to compensate for impaired AM competence but ROS deficiency has no apparent effect on AM function in this model. |
| 2 | 21896326 | Production of reactive oxygen species (ROS) resulting from phagocytic NADPH oxidase (NOX2) activity has been reported to contribute to host defense against numerous microbial pathogens. |