- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: DDX58
Gene name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
HGNC ID: 19102
Synonyms: RIG-I, FLJ13599, DKFZp434J1111
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IFNA1 | 1 hits |
| 2 | IRF3 | 1 hits |
| 3 | NFKB1 | 1 hits |
| 4 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19922606 | In the current study, we demonstrated that RIGI serves as a PRR in HPIV3 infected cells to induce innate antiviral response by expressing IFNbeta (via activation of interferon regulatory factor-3 or IRF3) and TNFalpha (via activation of NF-kappaB). |
| 2 | 20042593 | In this study, we investigated the abilities of two prototype strains of HMPV (A1 [NL1 0] and B1 [NL199]) to activate RIG-I and induce type I IFNs. |
| 3 | 20042593 | The failure of the HMPV-B1 strain to elicit type I IFN production was dependent on the B1 phosphoprotein, which specifically prevented RIG-I-mediated sensing of HMPV viral 5' triphosphate RNA. |
| 4 | 21106745 | Activation of RIG-I leads to type I interferon (IFN) and inflammatory cytokine production through interferon promoter stimulator 1 (IPS-1)-mediated activation of interferon regulatory factor 3 (IRF3) and NF-?B signaling. |
| 5 | 18548002 | RIG-I binds PAMP RNA and signals interferon regulatory factor 3 activation to induce the expression of interferon-alpha/beta and antiviral/interferon-stimulated genes (ISGs) that limit infection. |
| 6 | 21303708 | As an adaptor molecule in the retinoic acid-inducible gene-I (RIG-I) signaling pathway, the virus-induced signaling adaptor (VISA) molecule activates NF-?B and IRF3 and thereby leads to the production of type I interferons (IFNs). |