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Gene Information
Gene symbol: EGFR
Gene name: epidermal growth factor receptor
HGNC ID: 3236
Synonyms: ERBB1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AREG | 1 hits |
| 2 | CD4 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | EGF | 1 hits |
| 5 | EGR1 | 1 hits |
| 6 | EREG | 1 hits |
| 7 | FOLH1 | 1 hits |
| 8 | HBEGF | 1 hits |
| 9 | IL1B | 1 hits |
| 10 | MT1E | 1 hits |
| 11 | NRG1 | 1 hits |
| 12 | TGFA | 1 hits |
| 13 | TNF | 1 hits |
| 14 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8562166 | Our data demonstrate the IFN gamma, TNF alpha and IL-1 alpha can decrease the expression of EGFR on some bladder tumour cell lines. |
| 2 | 15838380 | Depletion of CD4+ T lymphocytes could completely abrogate the antitumor activity and EGFR-specific antibody responses, whereas the depletion of CD8+ T lymphocytes showed partial abrogation of the antitumor activity but antibody was still detected. |
| 3 | 16328386 | Transforming growth factor alpha (TGFalpha) is a potent ligand of the epidermal growth factor receptor (EGFR). |
| 4 | 16328386 | EGFR is frequently over-expressed in epithelial tumors and endogenous ligands, mostly TGFalpha, are frequently co-expressed with EGFR, potentially resulting in autocrine stimulation of tumor cell growth. |
| 5 | 18552348 | Neuregulin 1 activates ERBB receptors releasing a factor, EBP1, known to inhibit the influenza virus transcriptase. |
| 6 | 19752336 | PURPOSE To evaluate the maximum-tolerated dose (MTD), safety profile, and immunogenicity of two chimeric, B-cell epitopes derived from the human epidermal growth factor receptor (HER2) extracellular domain in a combination vaccine with a promiscuous T-cell epitope (ie, MVF) and nor-muramyl-dipeptide as adjuvant emulsified in SEPPIC ISA 720. |
| 7 | 20190820 | Egr-1 increased the transcription of HB-EGF (epidermal growth factor), amphiregulin and epiregulin, resulting in autocrine activation of the EGF receptor (EGFR) and downstream MEK/ERK cascade. |
| 8 | 20190820 | Finally, p53 may further regulate this feedback loop by altering the level of EGFR expression. |
| 9 | 21282736 | Levels of mRNA encoding PSMA were significantly elevated following treatment with the bispecific oligos (directed against both BCL-2 and the epidermal growth factor receptor) but not by the monospecific directed solely against BCL-2. |