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Gene Information
Gene symbol: GATA3
Gene name: GATA binding protein 3
HGNC ID: 4172
Synonyms: HDR
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | FOXP3 | 1 hits |
| 3 | PIK3CA | 1 hits |
| 4 | TBX21 | 1 hits |
| 5 | WAS | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15833169 | In comparison with BCG-naive mice, T-bet was significantly high in BCG-vaccinated mice [T-bet/beta-actin 0.44 +/- 0.11 vs. 0.28 +/- 0.06, P < 0.05], but there was no significant difference in GATA-3 [GATA-3/beta-actin 0.46 +/- 0.08 vs. 0.50 +/- 0.10,P > 0.05] and Foxp3 [Foxp3/beta-actin vs. 0.27 +/- 0.11 and 0.30 +/- 0.16, P > 0.05] mRNA expression between the two groups. |
| 2 | 20072623 | After in vitro stimulation, spleen cells of immunized mice produce high levels of Th1 cytokines and show a prominent mRNA expression of the Th1 transcription factor T-bet, in detriment of the Th2 transcription factor GATA-3. |
| 3 | 20696860 | Thus, TCR signaling through PI3K may play a critical role in Th2 differentiation by the specific enhancement of GATA-3 translation. |
| 4 | 21079691 | We found that the Th1 subset dominated the UGT, as IFN-? and T-bet mRNA expression were high, while GATA-3 was low following genital infection with C. trachomatis serovar D. |
| 5 | 20032499 | WAS(-/-) CD4(+) T cells up-regulated IL-4 and GATA3 mRNA and secreted IL-4 protein during Th2 differentiation. |
| 6 | 20032499 | WAS(-/-) Th2s failed to produce IL-4 protein on restimulation despite elevated IL-4/GATA3 mRNA. |