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Gene Information
Gene symbol: IFIH1
Gene name: interferon induced with helicase C domain 1
HGNC ID: 18873
Synonyms: MDA-5, Hlcd, MDA5, IDDM19
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CXCL10 | 1 hits |
| 2 | STAT1 | 1 hits |
| 3 | TLR3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17537851 | The expression profiles of transcription factors such as NF-kappaB/Rel and STAT were regulated similarly by both viruses; in contrast, OASL, MDA5, and IRIG-I expression increased only during MVA infection. |
| 2 | 19995959 | Interestingly, multiple accessory cells were implicated, with MDA5 acting primarily in stromal cells and TLR3 predominantly in hematopoietic cells. |
| 3 | 21728171 | Monocytes and monocyte-derived DCs (MoDCs) engulfed MDA-5-activated cancer cells, and subsequently upregulated HLA-class I/II and costimulatory molecules, and secreted CXCL10 and IFN-?. |