- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: IKZF2
Gene name: IKAROS family zinc finger 2 (Helios)
HGNC ID: 13177
Synonyms: Helios
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CXCR5 | 1 hits |
| 3 | IL13 | 1 hits |
| 4 | IL4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21677778 | Here, we show that mouse ovalbumin-specific CD4 (OTII) cells responding to alum-precipitated ovalbumin (alumOVA) upregulate Th2 features - GATA-3 and IL-4 - as well as Helios mRNA and protein. |
| 2 | 21677778 | In addition, CD4 T cells induced to produce Th2 cytokines in vitro do not express Helios. |
| 3 | 21677778 | The induction of IL-4, IL-13 and CXCR5 by alumOVA requires NF-?B1 and this is also needed for Helios upregulation. |
| 4 | 21677778 | Helios is selectively upregulated in CD4 T cells during Th2 and TFh responses to alum-protein vaccines in vivo, but the functional significance of this upregulation remains uncertain. |