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Gene Information
Gene symbol: IRF6
Gene name: interferon regulatory factor 6
HGNC ID: 6121
Synonyms: OFC6, VWS1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD80 | 1 hits |
| 2 | HLA-A | 1 hits |
| 3 | IFNG | 1 hits |
| 4 | IL10 | 1 hits |
| 5 | IL2RA | 1 hits |
| 6 | IL4 | 1 hits |
| 7 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2787716 | It is concluded that, following vaccination with PPS increased IL-2R expression is induced on blood lymphocytes. |
| 2 | 19785053 | Surprisingly, LPS and NDV had opposite effects on induction of interferon (IFN)-alpha. |
| 3 | 19785053 | Furthermore, NDV induced DC maturation (as measured by TNF-alpha production and CD80 cell surface expression) only in the presence of LPS. |
| 4 | 19785053 | Most interestingly, an optimal combination of NDV and LPS caused polarization of the DCs to Th1 type cytokines with a high ratio of interleukin (IL)-12 to IL-10. |
| 5 | 19818956 | However, we found that 48h DC were more susceptible than SDDC to the IL-10 inducing stimulus of TLR ligands (R848 and LPS). |
| 6 | 21569812 | Allogeneic LPS-matured DC-TC hybrids induced high IFN-? levels, but concomitantly also the highest production of IL-4 and IL-10 suggesting activation of mechanisms sustaining regulatory cells able to blunt vaccine efficacy. |
| 7 | 21592111 | DCs modified with siRNA targeting against IL-10R or IL-10 (DC/siIL-10R or DC/siIL-10) led to up-regulation of major histocompatibility complex (MHC) class II, CD40 co-stimulatory molecule, and IL-12 proinflammatory cytokine after lipopolysacharide (LPS) stimulation compared to DC/siGFP. |