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Gene Information

Gene symbol: IRF7

Gene name: interferon regulatory factor 7

HGNC ID: 6122

Related Genes

# Gene Symbol Number of hits
1 IFNB1 1 hits
2 IFNG 1 hits
3 TLR9 1 hits
4 TRIM63 1 hits

Related Sentences

# PMID Sentence
1 19515829 Our results indicate that infection with amplicons triggered an interferon (IFN)-regulatory factors 3 and 7 (IRF3/7)-dependent antiviral response, rendered the cells resistant to vesicular stomatitis virus infection and induced significant changes in the pattern of cellular gene expression, including the upregulation of Toll-like receptor 3 (TLR3), IRF7 and IFN-stimulated genes (ISGs).
2 20432465 Here we report an approach to enhance the immunogenicity of DNA vaccines involving the use of transcription factors of the Interferon regulatory factor (IRF) family, specifically IRF-1, IRF-3, and IRF-7 using the tat gene as model antigen.
3 19880818 Similarly, the expression of IRF7, a key transcription factor controlling the expression of IFN-alpha, was significantly decreased in influenza-infected and IFN-beta-stimulated NECs from smokers.
4 21134826 First, HBV DNA can be recognized by DCs through toll-like receptor 9 (TLR9) which activates the NF-?B signal pathway and p38 MAPK to up-regulate the expression of interferon (IFN) regulatory factor 7 (IRF-7) in a manner independent of type I IFN signaling, resulting in secretion of type I IFN and inflammatory cytokines, and induction of DC maturation and the adaptive immune response.