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Gene Information

Gene symbol: ISG20

Gene name: interferon stimulated exonuclease gene 20kDa

HGNC ID: 6130

Synonyms: HEM45, CD25

Related Genes

# Gene Symbol Number of hits
1 CD4 1 hits
2 CD40 1 hits
3 IL10 1 hits
4 SELL 1 hits
5 TGS1 1 hits
6 TH1L 1 hits

Related Sentences

# PMID Sentence
1 9341744 In contrast, we noted an increase in the IL-4-producing CD4+ T cells that also exhibited the memory phenotype, CD45RO, and an upregulated expression of CD25 in cultures from malaria protected persons as compared to malaria naive persons and subjects who became parasitemic.
2 9341744 Hence, these observations suggest that the induction of memory CD4+ T cell subset distinguished by the expression of CD45RO and CD25 and production of IL-4 coincides with protective immune responses generated by immunization with attenuated SPZ.
3 17429840 When stimulated with antigen, they decreased CD62L, increased CD44 and CD25, and had no change in CD45RO expression.
4 17651141 The production of Th1 cytokines, but not Th2 cytokines, was suppressed by CD4+CD25+ cells from both allergic patients and controls, upon stimulation with birch pollen extract.
5 17954761 Lymph node cell populations stimulated with ovalbumin had decreased CD5, CD21, and CD40 expression and increased B-B2, CD25, and CD80 expression on IgM+ cells.
6 21059286 Immune non-response to HBV vaccination may be connected to insufficient secretion of IFNgamma; There was no correlation between the titer of anti-HBs and the expressions of IFNgamma and CD4+CD25+ Foxp3.
7 20977501 Furthermore, depletion assays suggest that CD4(+) CD25(+) T cells are involved in PPD-stimulated IL-10 secretion in response to BCG vaccination.
8 21220773 However, after direct TCR stimulation, naive CD4 T cells from HCV-infected patients had altered up-regulation of KI67 and CD25 and less CD27 expression.
9 17346430 The question of whether T cell responses to SEREX-defined tumor antigens are under regulation of naturally occurring CD4+CD25+ regulatory T cells (nTreg cells) has not been answered.