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Gene Information
Gene symbol: ITGAX
Gene name: integrin, alpha X (complement component 3 receptor 4 subunit)
HGNC ID: 6152
Synonyms: CD11c
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL2 | 1 hits |
| 2 | CCR6 | 1 hits |
| 3 | CD40 | 1 hits |
| 4 | CD80 | 1 hits |
| 5 | CD86 | 1 hits |
| 6 | HLA-A | 1 hits |
| 7 | IL10 | 1 hits |
| 8 | IL3RA | 1 hits |
| 9 | IL6 | 1 hits |
| 10 | IL8 | 1 hits |
| 11 | PIK3R1 | 1 hits |
| 12 | TNF | 1 hits |
| 13 | TNPO1 | 1 hits |
| 14 | VEGFA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10792499 | The expression of major histocompatibility complex class II, CD80, CD86 and CD11c by BMDC after phagocytosing rBCG or inert beads, was inhibited when the BMDC were pretreated with IL-10. |
| 2 | 15384929 | FL induced increases in immature CD11c+ and CD123+ peripheral blood (PB) DCs. |
| 3 | 18208592 | On the other hand, DCs, characterized as CD11c+/CD86+/CD123-/BDCA-4+/IFN-alpha-, produced high levels of IL-12 and low levels of TNF-alpha, IL-6 and IL-10. |
| 4 | 19237318 | Furthermore, during the MDDC differentiation process, high doses of alpha-defensins1-3 affected CD14, CD11c and CD86 expression and strongly up-regulated IL-8. |
| 5 | 19414774 | In this study, we used the freshly isolated tumor cells to mimic tumor microenvironment to coculture DCs and found that the freshly isolated tumor cells could drive DCs to differentiate into regulatory DCs with a CD11c(low)CD11b(high)Ia(low) phenotype and high expression of IL-10, NO, vascular endothelial growth factor, and arginase I. |
| 6 | 20502628 | Furthermore, increased frequencies of CD11c(+)B220(+) DCs and CD11c(+)CD11b(+) DCs with up-regulated expression of CD80, CD86, CD40 and MHC II molecules were noted in spleen, Peyer's patches and cervical lymph nodes. |
| 7 | 19799079 | B220(-) CD11c+ cells increased obviously after MIP-1 alpha injection, and freshly isolated B220(-) CD11c+ cells cultured with mGM-CSF, IL-4, and mTNF-alpha were phenotypically identical to typical DC, gained the capacity to stimulate allogeneic T cells. |
| 8 | 19064283 | Furthermore, DNA/P85 and P85 alone increase the systemic expansion of CD11c+ (DC), and local expansion of CD11c+, CD14+ (macrophages) and CD49b+ (natural killer) cell populations. |
| 9 | 21115722 | Furthermore, increased numbers of CD11c(+) CD8?(+), but not CD11c(+) CD11b(+) or CD11c(+) B220(+), dendritic cells with upregulated expression of CD80, CD86, CD40, and major histocompatibility complex class II (MHC II) molecules were noted in the spleen, CLNs, and nasopharynx-associated lymphoreticular tissues (NALT). |
| 10 | 19124765 | Typhi(F1) enhanced the activation and maturation of neonatal CD11c+ dendritic cells, shown by increased expression of CD80, CD86, CD40, and MHC-II cell surface markers and production of proinflammatory cytokines IL-12, TNF-alpha, IL-6, and MCP-1. |
| 11 | 21453265 | CD11c, CD40, Fc?, CCR6, pathogenic recognition receptors such as Toll-like receptors (TLRs) and C-type lectin receptors (CLRs)). |