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Gene Information
Gene symbol: JAK1
Gene name: Janus kinase 1
HGNC ID: 6190
Synonyms: JAK1A, JTK3
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYP3A4 | 1 hits |
| 2 | IFNG | 1 hits |
| 3 | MAPK14 | 1 hits |
| 4 | STAT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19656875 | Furthermore, at times when STAT1 activation was efficiently inhibited, VRP infection did not limit tyrosine phosphorylation of Jak1, Tyk2, or STAT2 after IFN-beta treatment but did inhibit Jak1 and Jak2 activation in response to IFN-gamma, suggesting that VEEV interferes with STAT1 activation by the type I and II receptor complexes through distinct mechanisms. |
| 2 | 20739538 | Decreased STAT activation in AR86-infected cells was associated with decreased activation of the IFN receptor-associated tyrosine kinases Tyk2, Jak1, and Jak2. |
| 3 | 21466820 | Pharmacologic inhibitors and a dominant-negative mutant expression plasmid were used to dissect the molecular pathway required for CYP3A4 suppression, revealing roles for Jak1 and Stat1 and eliminating the involvement of the p38 mitogen-activated and extracellular regulated kinases. |