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Gene Information
Gene symbol: KIT
Gene name: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
HGNC ID: 6342
Synonyms: CD117, SCFR, C-Kit
Related Genes
Related Sentences
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PMID |
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21106069
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Both human and mouse HPCs were expanded first in feeder culture supplemented with c-Kit ligand (KL, stem cell factor, steel factor or CD117 ligand), Flt3 ligand (fms-like tyrosine kinase 3, Flt3L, FL), thrombopoietin (TPO), IL-3, IL-6, and basic fibroblast growth factor (bFGF), and then in a second feeder culture ectopically expressing all above growth factors plus GM-CSF and IL-15.In the dual culture system, CD34+ HPCs differentiated toward DC progenitors (DCPs), which expanded more than five orders of magnitude.
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