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Gene Information
Gene symbol: KLRG1
Gene name: killer cell lectin-like receptor subfamily G, member 1
HGNC ID: 6380
Synonyms: MAFA, 2F1, MAFA-L, CLEC15A
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD27 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | EOMES | 1 hits |
| 4 | TBX21 | 1 hits |
| 5 | TNFRSF9 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18424713 | Further phenotypic analysis revealed that the acquisition of KLRG1 among effector subpopulations correlated with the down-regulation of both IL-7R and CD27, suggesting that KLRG1 marks dominant, end-stage effector cells. |
| 2 | 18424713 | Furthermore, IL-12 signaling-dependent T-bet expression was also found to be important for differentiation of KLRG1(+) effectors. |
| 3 | 21422297 | Subsets of T cells could be defined based on their expression of Eomes, Cxcr3, and Ccr7, or Klrk1, Klrg1, and Ccr5 in CM and EM cells, respectively. |
| 4 | 21559358 | Anti 4-1BB treatment, with or without CTLA-4 blockade, induced approximately 75% of CD8+ and 45% of CD4+ effector T-cells in the tumor to express the killer cell lectin-like receptor G1 (KLRG1). |