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Gene Information
Gene symbol: KRR1
Gene name: KRR1, small subunit (SSU) processome component, homolog (yeast)
HGNC ID: 5176
Synonyms: RIP-1
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
18941233
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DAI binds to and colocalizes with endogenous RIP1 at characteristic cytoplasmic granules.
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2 |
18941233
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Suppression of RIP1 expression by RNAi abrogates NF-kappaB activation as well as IFNbeta induction by immunostimulatory DNA.
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3 |
18941233
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The role of DAI in activation of NF-kappaB in response to immunostimulatory DNA appears to be analogous to sensing of dsRNA by TLR3 in that both pathways involve RHIM-dependent signaling that is mediated via RIP1, reinforcing a central role for this adaptor in innate sensing of intracellular microbes.
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