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Gene Information
Gene symbol: LTA
Gene name: lymphotoxin alpha (TNF superfamily, member 1)
HGNC ID: 6709
Synonyms: TNFSF1, LT
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD80 | 1 hits |
| 2 | CD86 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | HBB | 1 hits |
| 5 | IL10 | 1 hits |
| 6 | MUC1 | 1 hits |
| 7 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11907234 | Our studies showed that LCMV-infected LTalpha(-/-) mice had a profound impairment in the activation and expansion of virus-specific CD8 T cells in the spleen, as determined by cytotoxicity assays, intracellular staining for gamma interferon, and staining with major histocompatibility complex class I tetramers. |
| 2 | 18632923 | Previous studies showed that LTA also synergizes with hemoglobin. |
| 3 | 19278729 | Stimulation with TNF, S. gordonii, PGN, LTA, or LP all resulted in increased surface expression of MHCII, CD80, and CD86, compared to unstimulated BM-DCs. |
| 4 | 20720206 | We show that a rapid increase in parasite biomass is strongly associated with the induction of ECM, mediated by IFN-gamma and lymphotoxin alpha, whereas TNF and IL-10 limit this process. |
| 5 | 20334603 | The LTA anchored PLGA nanoparticles have demonstrated approximately four-fold increase in the degree of interaction with the bovine submaxillary mucin (BSM). |
| 6 | 20826612 | Although the levels of expression of the inflammatory cytokines tumor necrosis factor alpha (TNF-?) and IL-1? were increased by LTA and MDP at the mRNA level, no protein could be detected in the bMEpC culture supernatant. |