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Gene Information
Gene symbol: LTF
Gene name: lactotransferrin
HGNC ID: 6720
Synonyms: HLF2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD40 | 1 hits |
| 2 | CD80 | 1 hits |
| 3 | CD86 | 1 hits |
| 4 | COL1A1 | 1 hits |
| 5 | CXCL2 | 1 hits |
| 6 | HLA-A | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | IL10 | 1 hits |
| 9 | IL12A | 1 hits |
| 10 | IL15 | 1 hits |
| 11 | TBPL2 | 1 hits |
| 12 | TF | 1 hits |
| 13 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 7752881 | Whereas the LbpA protein shows homology to the transferrin-binding protein 1 (Tbp1), the putative protein encoded by the open reading frame upstream of IbpA shows extensive homology to Tbp2, suggesting that iron-acquisition from lactoferrin, like from transferrin, requires two specific proteins in the outer membrane. |
| 2 | 8939794 | Most strains expressed low binding of iodine-labeled human fibronectin, collagen I and IV, and higher binding of human vitronectin, human lactoferrin, and human thrombospondin. |
| 3 | 11962727 | J774A.1 murine macrophages stimulated with Lactoferrin resulted in increased TNF-alpha protein production, and upregulated IL-12 and IL-15 mRNA. |
| 4 | 17507876 | In addition, BCG-infected cells incubated in the presence of lactoferrin demonstrated a significant increase in relative IL-12 to IL-10 ratios in a dose-dependent manner. |
| 5 | 18486627 | Lactoferrin treated BCG-infected BMMs were able to stimulate an increase in IFN-gamma production from presensitized CD3(+) splenocytes. |
| 6 | 19692539 | In this study, the potential of lactoferrin to modulate surface expression of MHC II, CD80, CD86 and CD40 from bone marrow-derived dendritic cells (BMDCs) was examined. |
| 7 | 19692539 | Generally, lactoferrin decreased pro-inflammatory cytokines [tumor necrosis factor (TNF)-alpha, IL-6 and IL-12p40] and chemokines [macrophage inflammatory protein (MIP)-1alpha and MIP-2] and increased regulatory cytokine, transforming growth factor-beta1 and a T-cell chemotatic factor, monocyte chemotactic protein-1, from uninfected or BCG-infected BMDCs. |
| 8 | 19692539 | Culturing BCG-infected BMDCs with lactoferrin also enhanced their ability to respond to IFN-gamma activation through up-regulation of maturation markers: MHC I, MHC II and the ratio of CD86:CD80 surface expression. |