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Gene Information
Gene symbol: LY75
Gene name: lymphocyte antigen 75
HGNC ID: 6729
Synonyms: DEC-205, CLEC13B, CD205
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD70 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | CTAG1B | 1 hits |
| 5 | IL10 | 1 hits |
| 6 | IL12A | 1 hits |
| 7 | IL4 | 1 hits |
| 8 | MSLN | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9341783 | Therefore, we analyzed the C26 murine colon carcinoma genetically modified to release interleukin (IL)-2, IL-4, IL-12, granulocyte colony-stimulating-factor (CSF) or granulocyte-macrophage (GM)-CSF for immunostaining with the monoclonal antibody NDLC145 recognizing the DEC205 determinant which, on tumor sections, is virtually restricted to DC. |
| 2 | 17438065 | This pathway requires the membrane-associated tumor necrosis family member CD70 and was identified by targeting the LACK antigen from Leishmania major within an antibody to CD205 (DEC-205), an uptake receptor on a subset of DCs. |
| 3 | 17438065 | Isolated CD205(+) DCs expressed cell surface CD70 when presenting antigen to T cell receptor transgenic T cells, and this distinction was independent of maturation stimuli. |
| 4 | 19769731 | Targeting human MSLN to DEC-205 receptor induced stronger CD4(+) T-cell responses compared to high doses of mesothelin protein. |
| 5 | 19769731 | In summary, targeting of MSLN to DEC-205 improves the induction of CD4(+) and CD8(+) T-cell immunity accompanied by an antibody response. |
| 6 | 20566893 | DEC-205, a phagocytosis receptor mediating antigen uptake, is associated with CD8(+) T-cell responses in mice. |
| 7 | 21149605 | We generated two novel targeting proteins consisting of the full-length NY-ESO-1 fused to the C terminus of two human mAbs against the human mannose receptor and DEC-205, both internalizing molecules expressed on APC. |
| 8 | 21262534 | Strikingly, nanoparticle surface density of DEC-205 mAb increased the amount of anti-inflammatory, IL-10, produced by DCs and T cells. |
| 9 | 21262534 | Boosting mice with DEC-205 targeted OVA-nanoparticles after immunization with an antigen in CFA induced a similar pattern of IL-10 response. |