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Gene Information
Gene symbol: MAPK3
Gene name: mitogen-activated protein kinase 3
HGNC ID: 6877
Synonyms: ERK1, p44mapk, p44erk1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AKT1 | 1 hits |
| 2 | CCL5 | 1 hits |
| 3 | MAPK1 | 1 hits |
| 4 | PIK3CA | 1 hits |
| 5 | PTK2B | 1 hits |
| 6 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16641451 | Herein, we show that SAG induces extracellular signal-regulated kinase 1 (ERK-1) and ERK-2 phosphorylation through phosphoinositide 3-kinase (PI3K), protein kinase C, and Ras activation and p38 mitogen-activated protein kinase (MAPK) phosphorylation through PI3K and Akt activation. |
| 2 | 16641451 | ERK-1 and ERK-2 activation results in an increase in the production of reactive oxygen species (ROS) 3 to 6 h after SAG treatment, while p38 MAPK activation and subsequent tumor necrosis factor alpha release result in the production of nitric oxide (NO) 24 h after SAG treatment. |
| 3 | 19229316 | While US28 binding of both RANTES and Fractalkine activate FAK and ERK-1/2, RANTES signals through Galpha12 and Fractalkine through Galphaq. |
| 4 | 18287580 | PorB was able to induce (i) protein tyrosine kinase (PTK) activity, (ii) the phosphorylation of Erk1 and Erk2, and (iii) IkappaB-alpha phosphorylation, leading to NF-kappaB nuclear translocation in B cells in a TLR2-dependent manner. |