Gene Information
Gene symbol: MDM2
Gene name: Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
HGNC ID: 6973
Synonyms: HDM2, HDMX, MGC5370
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
21444629
|
Our objective was to evaluate cell growth and death effects by inhibiting Murine Double Minute 2 (MDM2) expression in human prostate cancer cells overexpressing the wild-type (WT) p53 gene.
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2 |
21444629
|
These results suggest that knockdown of mdm2 expression by its specific small interfering RNA with overexpression of the WT p53 gene offers synergistic inhibition of prostate cancer cell growth in vitro and in vivo.
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