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Gene Information
Gene symbol: NCR1
Gene name: natural cytotoxicity triggering receptor 1
HGNC ID: 6731
Synonyms: NK-p46, NKP46, CD335
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD244 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | IL2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16275895 | Bovine natural killer (NK) cells were recently identified by positive selection of a NK cell-activating receptor p46 (NKp46)+ CD3- lymphocyte population, which expresses CD25 and CD8 and lyses tumor cell lines following stimulation with recombinant interleukin-2. |
| 2 | 21214542 | Here, we show that upon in vitro exposure to influenza, NKp46 expression on NK cells decreases, whereas expression of 2B4, an activating receptor that can enhance natural cytotoxicity in synergy with NKp46, is up-regulated. |
| 3 | 21214542 | Altogether, our results further suggest that NKp46 may play an important role in the innate immune response to human influenza and reveal that exposure to influenza antigens is associated with a previously unrecognized increase in 2B4 expression that can impact NK cell activity against the virus. |