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Gene Information
Gene symbol: NFKBIA
Gene name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
HGNC ID: 7797
Synonyms: IKBA, MAD-3, IkappaBalpha
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EIF2AK2 | 1 hits |
| 2 | NFKB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19596385 | In human embryonic kidney (HEK 293T) cells, the MVA-induced depletion of IkappaBalpha required to activate NF-kappaB is inhibited by UV-inactivation of the virus, and begins before viral DNA replication. |
| 2 | 19596385 | In mouse embryonic fibroblasts (MEFs), MVA induction of IkappaBalpha depletion is dependent on the expression of mouse or human double-stranded RNA-activated protein kinase (PKR). |
| 3 | 20504922 | This domain has the ability to inhibit NF-kappaB activation by interfering with the polyubiquitination process of IkappaBalpha, which subsequently prevents IkappaBalpha degradation. |