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Gene Information
Gene symbol: NLRP3
Gene name: NLR family, pyrin domain containing 3
HGNC ID: 16400
Synonyms: AGTAVPRL, AII, AVP, FCAS, FCU, NALP3, PYPAF1, MWS, CLR1.1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
18566365
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In this study we show that, in human and mouse macrophages, alum-induced secretion of IL-1beta, IL-18, and IL-33 is mediated by the NLR (nucleotide-binding domain leucine-rich repeat-containing) protein NLRP3 and its adaptor ASC, but not by NLRC4.
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2 |
18624356
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Importantly, induction of IgG production against human serum albumin by alum was unimpaired in mice deficient in Nlrp3.
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