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Gene Information
Gene symbol: PHIP
Gene name: pleckstrin homology domain interacting protein
HGNC ID: 15673
Synonyms: ndrp, FLJ20705, DCAF14, BRWD2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | FOS | 1 hits |
| 2 | IL2 | 1 hits |
| 3 | NFKB1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16168555 | Reverse transcription-polymerase chain reaction (RT-PCR) analysis demonstrated that PhIP attenuated IL-2 mRNA expression in the thymocytes and EL4 cells stimulated with phytohemagglutinin (PHA) plus phorbol 12-myristate 13-acetate (PMA). |
| 2 | 16168555 | These results suggest that PhIP has potential immunosuppressive effects by inhibiting T-cell proliferation and IL-2 expression through down regulation of ROS generation and thereby inhibiting NF-kappaB, AP-1 and NF-AT activation. |