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Gene Information
Gene symbol: PIK3R1
Gene name: phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
HGNC ID: 8979
Synonyms: GRB1, p85-ALPHA, p85
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD86 | 1 hits |
| 2 | ITGAX | 1 hits |
| 3 | PTPN11 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17170431 | Mutant virus encoding NS1 protein with mutations in the SH-binding motifs failed to interact with SH domains of p85 and did not activate the PI3K/Akt pathway. |
| 2 | 17170431 | Our study has established a novel function of NS1: by interacting with p85 via the SH-binding motifs, NS1 can activate the PI3K/Akt pathway. |
| 3 | 19064283 | Furthermore, DNA/P85 and P85 alone increase the systemic expansion of CD11c+ (DC), and local expansion of CD11c+, CD14+ (macrophages) and CD49b+ (natural killer) cell populations. |
| 4 | 19064283 | DNA/P85 (but not P85) also increases maturation of local DC (CD11c+ CD86+, CD11c+ CD80 +, and CD11c+ CD40+. |