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Gene Information

Gene symbol: PLAT

Gene name: plasminogen activator, tissue

HGNC ID: 9051

Related Genes

#	Gene Symbol	Number of hits
1	C20orf181	1 hits
2	INS	1 hits
3	PTPN11	1 hits
4	SERPINE1	1 hits
5	SERPINE2	1 hits

Related Sentences

#	PMID	Sentence
1	1367066	Almost half of them (OKT3, t-PA, and EPO) are produced in mammalian cells, with the remainder produced in bacteria (insulin, growth hormone, and alpha-interferon) or yeast (hepatitis vaccine).
2	11273882	Human peritoneal mesothelial cells (HMCs) have a critical role in maintaining the intraperitoneal balance between fibrinolysis and coagulation by expressing the fibrinolytic enzyme, tissue-type plasminogen activator (tPA), as well as a specific plasminogen activator inhibitor (type 1; PAI-1).
3	11273882	The increase in PAI-1 synthesis, not the decrease in the production of tPA, alters mesothelial fibrinolytic activity.
4	16122850	In order to evaluate the potential of a DNA vaccine based on the non-structural 1 (NS1) protein against dengue virus (DENV), we constructed the pcTPANS1 plasmid which contains the secretory signal sequence derived from human tissue plasminogen activator (t-PA) fused to the full length of the DENV-2 NS1 gene.
5	16140430	In order to investigate the potential of a DNA vaccine based on the NS1 protein against DENV, we used the plasmid pcTPANS1, which contains the secretory signal sequence derived from human tissue plasminogen activator (t-PA) fused to the full length of the DENV-2 NS1 gene.
6	20451569	We report here the successful immunization of mice with DNA vaccines expressing the secreted form of HEV-p179 (fused with a human tissue plasminogen activator (tPA) signal sequence) and the tPA-p179-C3d fusion protein (fused with three tandem copies of the murine complement C3d).