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Gene Information
Gene symbol: PPIA
Gene name: peptidylprolyl isomerase A (cyclophilin A)
HGNC ID: 9253
Synonyms: CYPA
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | IRF3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9465090 | Taken together with our observations that recombinant CyPA-induced mobilization of calcium in immortalized, as well as primary, CD4+ T lymphocytes, and that incubation of T cells with iodinated CyPA, followed by chemical cross-linking, resulted in the formation of a high molecular mass complex on the cell surface, these results suggest that HIV-1-associated CyPA mediates an early event in viral infection via interaction with a cellular receptor. |
| 2 | 20829794 | This innate response is dependent on the interaction of newly synthesized HIV-1 capsid with cellular cyclophilin A (CYPA) and the subsequent activation of the transcription factor IRF3. |