Ignet

Gene symbol: PSEN1

Gene name: presenilin 1

HGNC ID: 9508

Synonyms: FAD, S182, PS1

Related Genes

#	Gene Symbol	Number of hits
1	APLP2	1 hits

Related Sentences

#	PMID	Sentence
1	12230303	Some cases of AD are caused by mutations in presenilin-1 (PS1), and it has been shown that PS1 mutations perturb neuronal calcium homeostasis, promote increased production of amyloid beta-peptide (Abeta), and render neurons vulnerable to synaptic dysfunction, excitotoxicity, and apoptosis.