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Gene Information
Gene symbol: PTPRC
Gene name: protein tyrosine phosphatase, receptor type, C
HGNC ID: 9666
Synonyms: LCA, T200, GP180
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD14 | 1 hits |
| 2 | CD27 | 1 hits |
| 3 | CD274 | 1 hits |
| 4 | CD34 | 1 hits |
| 5 | CD4 | 1 hits |
| 6 | CD80 | 1 hits |
| 7 | CD86 | 1 hits |
| 8 | ITGAL | 1 hits |
| 9 | KIAA1279 | 1 hits |
| 10 | SULT1A3 | 1 hits |
| 11 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2830969 | Treatment of melanoma patients with CY plus vaccine resulted in a progressive fall in the proportion of CD4+ T-cells expressing the 2H4 (CD45) antigen, which identifies inducers of suppression. |
| 2 | 7489749 | Flow cytometric analysis of the cells during a 2-week culture revealed a loss of CD14 and CD34 expression, a concomittent increase of CD1a, CD11a,b and c, CD44, CD45, CD54, HLA-class I and II, and intermediate levels of CD26, CD80 and CD86. |
| 3 | 11260323 | In order to understand the mechanisms controlling the transcription of the human CD45 gene, 2.7 kbp of the 5'-flanking region were sequenced and analysed for their ability to direct expression of a reporter gene. |
| 4 | 16517710 | CD45(RO/+) cells produce more TNF-alpha and IFN-gamma. |
| 5 | 17641028 | In addition, LFA-1 is required for the recruitment and localization of talin into the peripheral supramolecular activation cluster region and exclusion of CD45 from the synapse. |
| 6 | 17641028 | The ability of LFA-1 to increase the amount of TCR engaged during synapse formation and segregate the phosphatase, CD45, from the synapse suggests that LFA-1 might enhance proximal TCR signaling. |
| 7 | 18426338 | In healthy individuals, the human peripheral blood CD27(+) B cell pool consists of two subsets defined by the expression, or lack thereof, of the CD45 isoform B220. |
| 8 | 18426338 | The AICD expression, along with CD86 expression, by CD27(+)B220(+) suggests these cells are of germinal center origin. |
| 9 | 19487686 | Here, we show STm rapidly induces a population of TI B220(+)CD5(-) B1b cells during infection and TI Ab from B1b cells targets the outer membrane protein (Omp) porins OmpC, OmpD and OmpF but not flagellin. |
| 10 | 19726615 | In our studies, cryopreservation significantly reduced the expression of both PD-1 and PD-L1 on PBMC-derived CD3+/CD8+ T cells and CD45+/CD14+ monocytes obtained from adult control subjects. |
| 11 | 20502628 | Furthermore, increased frequencies of CD11c(+)B220(+) DCs and CD11c(+)CD11b(+) DCs with up-regulated expression of CD80, CD86, CD40 and MHC II molecules were noted in spleen, Peyer's patches and cervical lymph nodes. |
| 12 | 21115722 | Furthermore, increased numbers of CD11c(+) CD8?(+), but not CD11c(+) CD11b(+) or CD11c(+) B220(+), dendritic cells with upregulated expression of CD80, CD86, CD40, and major histocompatibility complex class II (MHC II) molecules were noted in the spleen, CLNs, and nasopharynx-associated lymphoreticular tissues (NALT). |
| 13 | 19264552 | On day 40 after infection the fusion protein F36 and a pool of Ag85A and ESAT6 vaccines had significant effects on the bacterial load, showed increased expression of the activation marker CD45+ on CD4+ T cells, and reduced numbers of heterophils. |