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Gene Information
Gene symbol: STAT5A
Gene name: signal transducer and activator of transcription 5A
HGNC ID: 11366
Synonyms: MGF
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
20100932
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In this study, we found that CD86 was highly expressed on HCV-specific CD8(+) T cells early in acute HCV infection and was lost on transition to chronic HCV infection; the expression of CD86 was different from other activation markers, because expression was delayed after in vitro TCR stimulation and required sufficient IL-2 signaling; and HCV-specific CD8(+) T cells in the liver of patients with chronic HCV infection were highly activated (CD69, CD38, and HLA-DR expression), but only a minority expressed CD86 or showed evidence of recent IL-2 signaling (low basal phosphorylated STAT5), despite persistent viremia.
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2 |
18670213
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IL-15 predominantly activated STAT5, whereas IL-21 activated STAT5 and STAT3.
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3 |
20465573
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Responsiveness to IL-7 was gauged in a signal transducer and activation of transcription 5 (STAT-5) phosphorylation assay.
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