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Gene Information
Gene symbol: TLR7
Gene name: toll-like receptor 7
HGNC ID: 15631
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADAM11 | 1 hits |
| 2 | CD80 | 1 hits |
| 3 | CD86 | 1 hits |
| 4 | FOS | 1 hits |
| 5 | IFNA1 | 1 hits |
| 6 | IFNG | 1 hits |
| 7 | IL6 | 1 hits |
| 8 | MAPK8 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 14530357 | PDCs, which express TLR7 and TLR9, responded to imidazoquinolines (imiquimod and R-848) and to CpG oligodeoxynucleotides stimulation, resulting in enhancement in expression of costimulatory molecules and induction of IFN-alpha and IL-12p70. |
| 2 | 14530357 | In contrast, MDCs, which express TLR3, TLR4, and TLR7, responded to poly(I:C), LPS, and imidazoquinolines with phenotypic maturation and high production of IL-12 p70 without producing detectable IFN-alpha. |
| 3 | 18228247 | Synergistic production of IL-6 was observed in both human and mouse primary B cells stimulated through B cell antigen receptors, CD40 and TLR7, and these two receptors also cooperated independently of BCR signals. |
| 4 | 18228247 | Dual stimulation through CD40 and TLR7 markedly enhanced JNK activity. |
| 5 | 18228247 | The stimulation of B cells through both CD40 and TLR7 therefore enhanced the production of cytokines through increased JNK signaling and AP-1 activity. |
| 6 | 20605567 | When TLR7 signaling was inhibited, SV5 induced less IFN secretion and CD80 expression, and there was a corresponding increase in number of infected cells. |
| 7 | 21998589 | Remarkably, B cells in infected TLR7-deficient mice upregulated CD69 and CD86 early in infection, but failed to develop into germinal center B cells. |