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Gene Information
Gene symbol: TNFRSF13B
Gene name: tumor necrosis factor receptor superfamily, member 13B
HGNC ID: 18153
Synonyms: TACI, CD267
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CAMLG | 1 hits |
| 2 | CD19 | 1 hits |
| 3 | CD4 | 1 hits |
| 4 | CD8A | 1 hits |
| 5 | CELIAC3 | 1 hits |
| 6 | IFNG | 1 hits |
| 7 | SMCR | 1 hits |
| 8 | TNF | 1 hits |
| 9 | TNFRSF13C | 1 hits |
| 10 | TNFSF13B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21889412 | Therefore CMI responses were evaluated in 15 CVID-patients and 15 matched healthy controls (HC) by determining frequencies of interferon (IFN)?-producing PBMC, and frequencies of IFN?-, interleukin (IL)-2- and tumour necrosis factor (TNF)?-producing CD4+ and CD8+ T-cells before and after influenza vaccination using IFN? enzyme-linked immunospot (IFN?-ELISpot) and flow cytometry. |
| 2 | 16195331 | We demonstrated that B-cell-dendritic cell (DC) interactions via transmembrane activator and calcium modulator and cyclophilin ligand (CAML) interactor (TACI) and B-lymphocyte stimulator (BLyS) provide an early signal critical to generate adequate numbers of mature antigen presenting cells (APCs) to prime naive CD8(+) T cells (CTLs) in vivo. |
| 3 | 17538121 | TACI (transmembrane activator and calcium modulator and cyclophilin ligand [CAML] interactor) is a part of a novel network of ligands and receptors involved in B-cell survival and isotype switching. |
| 4 | 17538121 | The TACI protein mediates its effects through CAML, an endoplasmic reticulum (ER)-localized protein that controls Ca(2+) efflux. |
| 5 | 17538121 | Here, we provide evidence that E3-6.7K shares sequence homology with TACI and inhibits apoptosis and ER Ca(2+) efflux through an interaction with CAML, a Ca(2+)-modulating protein. |
| 6 | 17499850 | B cell activating factor belonging to the tumor necrosis factor (TNF) family (BAFF) is critical for B cell survival, maturation and T cell activation by acting through its three receptors, BAFF-R, BCMA and TACI. |
| 7 | 21306646 | Mice deficient for one of the three receptors for BLyS designated Transmembrane activator, calcium modulator, and cyclophilin ligand [CAML] interactor (TACI) exhibited attenuated PsaA-specific serum antibody responses following immunization with PsaA-BLyS relative to wild-type littermates. |
| 8 | 21514638 | We studied TACI expression and function in a cohort of 29 patients with SMS. |
| 9 | 21514638 | In patients with SMS with only 1 TACI allele, we found decreased B-cell extracellular and intracellular expression of TACI, reduced binding of a proliferation-inducing ligand, and decreased TACI-induced expression of activation-induced cytidine deaminase mRNA, but these were normal for cells from patients with SMS and 2 TACI alleles. |
| 10 | 21514638 | Patients with SMS with the lowest TACI expression had significantly reduced antibody responses to pneumococcal vaccine serotypes. |
| 11 | 19210517 | Mutations have been described in four genes, ICOS, CD19, BAFF-R and TNFRSF13B (encoding TACI), together associated with 10-15% of CVID cases. |