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Gene Information
Gene symbol: TNFRSF18
Gene name: tumor necrosis factor receptor superfamily, member 18
HGNC ID: 11914
Synonyms: AITR, GITR, CD357
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD40LG | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | SILV | 1 hits |
| 5 | TNFSF18 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16988005 | CD40 ligand (CD40L) and GITR ligand (glucocorticoid-induced tumor necrosis factor receptor-related protein ligand [GITRL]) are tumor necrosis factor superfamily molecules that can be used as vaccine adjuvants. |
| 2 | 19115935 | Glucocorticoid-induced tumor necrosis factor receptor (GITR) is a molecule that is constitutively expressed on CD4(+) Treg cells, and antibodies or natural ligands binding this molecule can impair Treg cell suppression. |
| 3 | 16651447 | We found that ligation of GITR with DTA-1 just before the second, but not the first, of 3 weekly DNA immunizations enhanced primary CD8(+) T-cell responses against the melanoma differentiation antigens gp100 and tyrosinase-related protein 2/dopachrome tautomerase and increased protection from a lethal challenge with B16 melanoma. |