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Gene Information
Gene symbol: TNFSF10
Gene name: tumor necrosis factor (ligand) superfamily, member 10
HGNC ID: 11925
Synonyms: TRAIL, Apo-2L, TL2, CD253
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL8 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | CFLAR | 1 hits |
| 4 | CXCL10 | 1 hits |
| 5 | EEF1B3 | 1 hits |
| 6 | FASLG | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | IGL | 1 hits |
| 9 | NEUROD1 | 1 hits |
| 10 | NOS2A | 1 hits |
| 11 | TGFA | 1 hits |
| 12 | TGFB2 | 1 hits |
| 13 | TGFB3 | 1 hits |
| 14 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10811870 | Type I IFNs induced a surprisingly rapid maturation of monocytes into short-lived tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-expressing DCs endowed with potent functional activities, superior with respect to the interleukin (IL)-4/GM-CSF treatment, as shown by FACS((R)) analyses, mixed leukocyte reaction assays with allogeneic PBLs, and lymphocyte proliferation responses to HIV-1-pulsed autologous DCs. |
| 2 | 12927083 | The candidate genes were: inducible nitric oxide synthase (INOS), tumor necrosis factor related apoptosis inducing ligand (TRAIL), transforming growth factor beta2 (TGF-beta2), transforming growth factor beta3 (TGF-beta3), and immunoglobulin G light chain (IgL). |
| 3 | 15150089 | Recent studies have shown CpG oligodeoxynucleotide induce tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression via IFN production. |
| 4 | 16081851 | This regimen prolonged survival of the animals and induced tumor-specific CTLs that expressed TRAIL, which in concert with perforin and Fas ligand (FasL) was involved in the tumor-specific CTL activity of these cells. |
| 5 | 16081851 | Transduction of the tumor cells with antiapoptotic protein cellular FLIP rendered the gene-modified cells resistant to TRAIL- or FasL-mediated apoptosis and to CTL killing activity in vitro. |
| 6 | 19551822 | MCP-2 and IP-10 levels were still elevated during the post-febrile period while TRAIL levels dropped close to normal after defervescense. |
| 7 | 20097864 | Multiple immune-effector molecules play a role in antimicrobial immunity mediated by memory CD8 T cells, including IFN-gamma, perforin, TRAIL, Fas ligand, and TNF-alpha. |
| 8 | 20810726 | Syncytia were also evident, along with significant basolateral secretion of proinflammatory chemokines, including IP-10, RANTES, tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), interleukin 6 (IL-6), and IL-8. |
| 9 | 18593617 | Findings from our laboratory have demonstrated that tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is induced by BCG treatment, and TRAIL was expressed on polymorphonuclear neutrophils (PMN) in the urine obtained from patients after intravesical BCG instillation. |
| 10 | 18593617 | Subsequently, we have determined that BCG and components of the mycobacterial cell wall can directly stimulate the release of soluble TRAIL from PMN through toll-like receptor-2 (TLR2) recognition that is augmented by interferon (IFN). |