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Gene Information
Gene symbol: TNFSF12
Gene name: tumor necrosis factor (ligand) superfamily, member 12
HGNC ID: 11927
Synonyms: TWEAK, DR3LG, APO3L
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL2 | 1 hits |
| 2 | TNFRSF12A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20068083 | Both 19.2.1 (mouse IgG2a) and PDL192 (human IgG1), like TWEAK, the natural ligand of TweakR, inhibited the growth of several TweakR-expressing cancer cell lines in anchorage-dependent and anchorage-independent assays in vitro. |
| 2 | 15652403 | TWEAK increased the secretion of CCL2 [monocyte chemotactic protein-1 (MCP-1)] by CNS endothelial cells and astrocytes in vitro, suggesting CCL2 as a critical mediator of TWEAKs proinflammatory effects. |
| 3 | 15652403 | Purified IgG from TWEAK- or Fn14-vaccinated rats prevented TWEAK-induced production of CCL2 by endothelial cells. |