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Gene Information
Gene symbol: TREM2
Gene name: triggering receptor expressed on myeloid cells 2
HGNC ID: 17761
Synonyms: TREM-2, Trem2a, Trem2b, Trem2c
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APLP2 | 1 hits |
| 2 | CCL2 | 1 hits |
| 3 | CD4 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | TMEM176B | 1 hits |
| 6 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20640189 | Tmem176b expression was highest in the inner zone of amyloid plaques, whereas TREM2 expression was highest in the outer zone. |
| 2 | 20640189 | Induced expression of TREM2 occurred co-incident with detection of thioflavine-S-positive amyloid deposits. |
| 3 | 20640189 | Transfection studies revealed that expression of TREM2 correlated negatively with motility, but correlated positively with the ability of microglia to stimulate CD4(+) T-cell proliferation, TNF (tumour necrosis factor) and CCL2 (chemokine ligand 2) production, but not IFNgamma (interferon gamma) production. |
| 4 | 20640189 | However, activating cells with LPS (lipopolysaccharide), but not IFNgamma, reduced the correlation between TREM2 expression and phagocytosis. |