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Gene Information

Gene symbol: TYK2

Gene name: tyrosine kinase 2

HGNC ID: 12440

Synonyms: JTK1

Related Genes

# Gene Symbol Number of hits
1 IFNB1 1 hits
2 IFNG 1 hits
3 STAT1 1 hits

Related Sentences

# PMID Sentence
1 19656875 Furthermore, at times when STAT1 activation was efficiently inhibited, VRP infection did not limit tyrosine phosphorylation of Jak1, Tyk2, or STAT2 after IFN-beta treatment but did inhibit Jak1 and Jak2 activation in response to IFN-gamma, suggesting that VEEV interferes with STAT1 activation by the type I and II receptor complexes through distinct mechanisms.
2 20739538 Decreased STAT activation in AR86-infected cells was associated with decreased activation of the IFN receptor-associated tyrosine kinases Tyk2, Jak1, and Jak2.