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Gene Information
Gene symbol: VEGFA
Gene name: vascular endothelial growth factor A
HGNC ID: 12680
Synonyms: VEGF-A, VPF
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD55 | 1 hits |
| 2 | ITGAM | 1 hits |
| 3 | ITGAX | 1 hits |
| 4 | MKI67 | 1 hits |
| 5 | NFKB1 | 1 hits |
| 6 | NRP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22059553 | Additional mice were treated systemically with antibodies engineered to specifically block the binding of VEGF to NRP1 (anti-NRP1B) and NRP2 (NRP2B), or the binding of semaphorins to NRP1 (anti-NRP1 A) to diminish activity of axon guidance molecules such as neuropilins (NRPs) and semaphorins (SEMAs). |
| 2 | 11139317 | Furthermore expression of CD55 on HUVEC cells was increased by exposure to VEGF. |
| 3 | 19414774 | In this study, we used the freshly isolated tumor cells to mimic tumor microenvironment to coculture DCs and found that the freshly isolated tumor cells could drive DCs to differentiate into regulatory DCs with a CD11c(low)CD11b(high)Ia(low) phenotype and high expression of IL-10, NO, vascular endothelial growth factor, and arginase I. |
| 4 | 19903839 | This was accompanied by a significant decrease in the proliferation marker Ki-67 (P < 0.01 versus control; P < 0.01 versus BCG alone) and microvessel density (CD31; P < 0.01 versus control; P < 0.01 versus BCG alone), decreased NF-kappaB in tumor tissue compared with the control, induced apoptosis, and decreased cyclin D1, vascular endothelial growth factor, cyclooxygenase-2, c-myc, and Bcl-2 expression in the tumor tissue. |
| 5 | 20861073 | For this purpose, we used neutralizing antibodies that were engineered to specifically block the binding of VEGF to NRP (anti-NRP1(B)) and the binding of semaphorins to NRP (anti-NRP1(A)). |