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Gene Information
Gene symbol: VHLL
Gene name: von Hippel-Lindau tumor suppressor-like
HGNC ID: 30666
Synonyms: VLP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL3 | 1 hits |
| 2 | CCL5 | 1 hits |
| 3 | CD4 | 1 hits |
| 4 | CD5 | 1 hits |
| 5 | CSF2 | 1 hits |
| 6 | ERVWE1 | 1 hits |
| 7 | IFNA1 | 1 hits |
| 8 | IL10 | 1 hits |
| 9 | IL2 | 1 hits |
| 10 | IL4 | 1 hits |
| 11 | IL6 | 1 hits |
| 12 | MIP | 1 hits |
| 13 | MUC1 | 1 hits |
| 14 | SPN | 1 hits |
| 15 | STAT1 | 1 hits |
| 16 | TNF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15944297 | HPV16 L1 VLP also activate production of proinflammatory factors IFN-alpha, IL-6, MIP-1alpha, RANTES, and KC, up-regulate the expression of costimulatory molecules by naive B cells, and increase the B1 B cell subpopulation. |
| 2 | 20652244 | MUC1-conjugated fully assembled VLPs induced robust activation of bone marrow-derived dendritic cells, which could then present MUC1 antigen to MUC1-specific T cell hybridomas and primary naïve MUC1-specific T cells obtained from a MUC1-specific TCR transgenic mice. |
| 3 | 20378136 | In an in vivo experiment, the murine cytokines induced by VLPs of naked DNA vaccine showed that the Th1 indicators IL-2, TNF-alpha and GM-CSF, and the Th2 indicators IL-4 and IL-10 were increased. |
| 4 | 21389873 | Immunization with mTrop2 VLPs led to a significant reduction in tumor growth accompanied by a broad activation and tumor infiltration of CD4(+) and CD8(+) T cells as well as natural killer and natural killer T cells. |
| 5 | 21651946 | In this study we propose that M2 protein can be used as a molecular fabricator without disrupting the assembly of VLPs and while retaining the native structures of HA and NA envelope protein oligomers on the particle surfaces. |
| 6 | 19376580 | VLPs stimulated the proliferation of B220(+)IgM(+)CD43(-)CD5(-) B2 cells and their differentiation to plasma cells that preferentially produce IgG2a antibodies. |
| 7 | 19376580 | Stimulation of naïve splenocytes with VLPs led to a high expression of IL-12, RANTES and MIP, the cytokine milieu that favors B cell differentiation into IgG2a secreting cells. |
| 8 | 21949376 | In addition, we show that murine IFN-? and human TNF-related apoptosis-inducing ligand can be displayed on the surface of VLPs, and that these modified VLPs can cause the appropriate response in cells, as evidenced by phosphorylation of STAT1 and induction of cell death, respectively. |