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Gene Information
Gene symbol: AADAC
Gene name: arylacetamide deacetylase
HGNC ID: 17
Synonyms: DAC, CES5A1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | IL2RA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19841877 | During T-cell activation in vitro, a DNA demethylation agent 5-Aza-2'-deoxycytydine (DAC) can induce Foxp3 expression in CD4(+)CD25(-) Foxp3(-) cells via altering methylation status of a conserved element in the 5'-untranslated region of the Foxp3 gene. |
| 2 | 19841877 | Thus, the in vivo treatment with DAC can significantly promote the development of natural thymic CD4(+)CD25(+)Foxp3(+) Treg cells through Foxp3 demethylation, implicating a therapeutic application of DAC in patients suffering from autoimmune diseases. |