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Gene Information
Gene symbol: ABCA4
Gene name: ATP-binding cassette, sub-family A (ABC1), member 4
HGNC ID: 34
Synonyms: FFM, ARMD2
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
12923232
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The LXR ligand T0901317 elevates ATP binding cassette transporter A1 (ABCA1) and HDL levels in animal models and induces moderate lipogenesis through upregulation of sterol regulatory element binding protein 1c (SREBP1c).
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2 |
20067955
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Abnormal cellular cholesterol handling in islets may contribute to beta-cell dysfunction in type 2 diabetes. beta-Cell deficiency for the ATP binding cassette transporter A1 (ABCA1), which mediates the efflux of cellular cholesterol, leads to altered intracellular cholesterol homeostasis and impaired insulin secretion in mice.
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