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Gene Information

Gene symbol: ABCG5

Gene name: ATP-binding cassette, sub-family G (WHITE), member 5

HGNC ID: 13886

Synonyms: STSL

Related Genes

# Gene Symbol Number of hits
1 ABCG8 1 hits
2 APOB 1 hits
3 HOXA11 1 hits
4 HOXB1 1 hits
5 MTTP 1 hits
6 NPC1L1 1 hits

Related Sentences

# PMID Sentence
1 12783625 ABCG5 and ABCG8 (encoding sterolin-1 and sterolin-2 respectively) have been shown to be responsible for causing sitosterolemia in humans.
2 16518588 We examined expression of the following: (1) Niemann-Pick C1-like 1 (NPC1L1), which regulates cholesterol absorption; (2) ATP-binding cassette transporters G5 and G8 (ABCG5, ABCG8), which regulate cholesterol homeostasis through their ability to excrete enterocyte cholesterol back into the lumen of the intestine; and (3) microsomal triglyceride transfer protein (MTTP), which packages the chylomicron particle by assembling cholesterol, triglyceride, phospholipids and apolipoprotein B48.
3 17109865 In diabetic animals, HMGCoA reductase, MTTP and NPC1L1 mRNA were significantly elevated (p<0.02) and ABCG5 and ABCG8 were significantly reduced (p<0.02) in the liver.
4 22046358 Genes involved in epigenetic processes, specifically homeobox genes (HOXA5, HOXA11, and HOXB1), and ABCG5 were among those that changed between diets.