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Gene Information
Gene symbol: ACADVL
Gene name: acyl-CoA dehydrogenase, very long chain
HGNC ID: 92
Synonyms: VLCAD, LCACD, ACAD6
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD36 | 1 hits |
| 2 | PPARA | 1 hits |
| 3 | PRKAA2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20723549 | Relative mRNA expression levels for lipid synthesis and transport including diacylglycerol acyltransferase (DGAT1/2), fatty acid translocase (CD36/FAT), fatty acid transport protein (FATP) were increased in pioglitazone-treated group compared to rosiglitazone-treated mice, but mRNA expression levels of ?-oxidation-related genes acyl-Coenzyme A dehydrogenase, very long chain (Acadvl), acyl-Coenzyme A dehydrogenase, medium chain (Acadm), and the energy expenditure-related genes triosephosphate isomerase 1 (Tpi1) and carnitine palmitoyltransferase 1b (Cpt1b) were decreased. these results suggest that pioglitazone activates lipid deposition by increasing lipid synthesis and transport, but rosiglitazone stimulates ?-oxidation and energy expenditure in adipocytes of db/db mice. |
| 2 | 20444420 | The increased insulin sensitivity in the VLCAD(-/-) mice were protected from diet-induced obesity and insulin resistance due to chronic activation of AMPK and PPARalpha, resulting in increased fatty acid oxidation and decreased intramyocellular and hepatocellular diacylglycerol content. |