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Gene Information
Gene symbol: ADCY1
Gene name: adenylate cyclase 1 (brain)
HGNC ID: 232
Synonyms: AC1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CRY1 | 1 hits |
| 2 | INS | 1 hits |
| 3 | PRKAA1 | 1 hits |
| 4 | PRKAR2A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20852621 | In biochemical reconstitution studies, we found that Cry1 inhibited accumulation of cAMP in response to G protein-coupled receptor (GPCR) activation but not to forskolin, a direct activator of adenyl cyclase. |
| 2 | 20188216 | Protein kinase A (PKA) is a multi-unit protein kinase that mediates signal transduction of G-protein-coupled receptors through its activation by adenyl cyclase (AC)-mediated cAMP. |
| 3 | 10909973 | Glucagon-like peptide 1 (GLP-1), a hormonal activator of adenyl cyclase, stimulates insulin gene transcription, an effect mediated by the cAMP response element (CRE) of the rat insulin I gene promoter (RIP1). |
| 4 | 19502419 | In keeping with this notion, IL-6 concurrently induced a transient increase in cAMP, and its ability to activate AMPK was blocked by the adenyl cyclase inhibitor 2'5'-dideoxyadenosine. |