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Gene Information
Gene symbol: AIFM1
Gene name: apoptosis-inducing factor, mitochondrion-associated, 1
HGNC ID: 8768
Synonyms: AIF
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
15054118
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The role of PARP in regulating AIF translocation in myocytes also was confirmed in an isolated perfused heart preparation.
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2 |
15054118
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Overall, the current results demonstrate the importance of the PARP pathway in diabetic rats subjected to myocardial infarction and demonstrate the role of PARP in regulating AIF translocation in MI/R.
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3 |
16728389
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Expression of iPLA2 in INS-1 cells prevented the loss of mitochondrial membrane potential, attenuated the release of cytochrome c, Smac/DIABLO, and apoptosis inducing factor from mitochondria, and reduced mitochondrial reactive oxygen species production.
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4 |
19094082
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Thus, nuclear translocation of AIF could underlie the increased death, whereas fragmentation of caspase 3 could be associated with the morphological changes found in hypothalamic astrocytes of diabetic rats.
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5 |
20832564
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The Ad5F35-SOCS1-infected islets with higher SOCS1 expression showed decreased levels of active caspase 3 and intranuclear AIF after treatment with tumor necrosis factor-? and cycloheximide in vitro.
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6 |
20832564
|
These results demonstrated that the expression of SOCS1 in islet grafts protected them from apoptosis through caspase 3 dependent and AIF caspase-independent-pathways.
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