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Gene Information
Gene symbol: ANXA5
Gene name: annexin A5
HGNC ID: 543
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ANXA7 | 1 hits |
| 2 | APLP2 | 1 hits |
| 3 | FGF2 | 1 hits |
| 4 | INS | 1 hits |
| 5 | NUDT6 | 1 hits |
| 6 | SNCA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2174439 | However, as with synexin, the dihydropyridine Ca2+ channel antagonist nifedipine does not affect endonexin II channel activity. |
| 2 | 2174439 | We conclude from these data that the domain responsible for endonexin II channel activity, first observed by ourselves in the homologue synexin, is probably the C-terminal tetrad repeat common to both molecules. |
| 3 | 8454101 | Our findings indicate that a gene on 4q, near the FABP2 and ANX5 loci, contributes to in vivo insulin action in Pima Indians. |
| 4 | 19810772 | In this study, we show that annexin A5 plays a role in interacting with and reducing the toxicity of the amyloidogenic proteins, h-IAPP and alpha-synuclein. |
| 5 | 19810772 | Experiments with transgenic expression of alpha-synuclein in Caenorhabditis elegans show that annexin A5 reduces alpha-synuclein inclusions in vivo. |
| 6 | 19810772 | Using thioflavin T fluorescence, electron microscopy, and electron paramagnetic resonance, we provide evidence that substoichiometric amounts of annexin A5 inhibit h-IAPP and alpha-synuclein misfolding and fibril formation. |
| 7 | 19810772 | We conclude that annexin A5 might act as a molecular safeguard against the formation of toxic amyloid aggregates. |
| 8 | 21249158 | In an independent experiment, insulin replacement therapy normalized the expression of some proteins (Dbi, Anxa5) while other proteins (Cp, Cryba3, Lgals3, Stat3) were only partially normalized and Fgf2 and Crybb2 expression remained elevated. |