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Gene Information
Gene symbol: ATF2
Gene name: activating transcription factor 2
HGNC ID: 784
Synonyms: TREB7, CRE-BP1, HB16
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BECN1 | 1 hits |
| 2 | CLDN5 | 1 hits |
| 3 | GABARAPL2 | 1 hits |
| 4 | INS | 1 hits |
| 5 | JUN | 1 hits |
| 6 | MAPK1 | 1 hits |
| 7 | MECP2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12149242 | SB 203580 (a p38 MAPK inhibitor) blocked ATF-2 phosphorylation, CRE transactivation, and c-jun promoter activation. |
| 2 | 12805110 | The transcription factor ATF-2, which is phosphorylated and activated by JNK and p38, also exhibited elevated retrograde axonal transport in STZ-diabetic animals (control 1.0 +/- 0.07, diabetic 3.0 +/- 0.41; P < 0.05). |
| 3 | 16873694 | Palmitic acid inhibits insulin signaling by promoting PTEN activity and its transcription through p38 and its downstream transcription factor ATF-2. |
| 4 | 21502138 | Furthermore, the CES-2-like basic region leucine-zipper (bZip) transcription factor ATF-2, an upstream modulator of the core apoptotic cell death pathway, is able to directly regulate the expression of at least two key autophagy-related genes, bec-1/ATG6 and lgg-1/ATG8. |
| 5 | 19742322 | Methylation did not directly inhibit factor binding to the CRE in vitro, but inhibited ATF2 and CREB binding in vivo and conversely increased the binding of methyl CpG binding protein 2 (MeCP2). |