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Gene Information
Gene symbol: ATR
Gene name: ataxia telangiectasia and Rad3 related
HGNC ID: 882
Synonyms: FRP1, SCKL, SCKL1, MEC1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADIPOQ | 1 hits |
| 2 | AKT1 | 1 hits |
| 3 | CHEK2 | 1 hits |
| 4 | H2AFX | 1 hits |
| 5 | IRS1 | 1 hits |
| 6 | TP53 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20736911 | This phosphorylation of H2AX is mediated by the phosphatidyl-inosito 3-kinase (PI3K) family of proteins, ataxia telangiectasia mutated (ATM), DNA-protein kinase catalytic subunit and ATM and RAD3-related (ATR). |
| 2 | 21123956 | Effects of ATR on the insulin resistance of age-matched (13-week-old) and unoperated KK/Ay mice were assessed by the glucose tolerance test, circulating adiponectin concentration, and changes in insulin signaling (IRS-1/Akt phosphorylation). |
| 3 | 21123956 | ATR was found to restore ischemic limb loss in diabetes by augmenting p53 degradation through direct activation of the Akt/MDM2 pathway in skeletal muscle. |
| 4 | 15187252 | The checkpoint kinase Chk2 is activated in response to DNA damage through pathways requiring protein kinases ATM and/or ATR. |