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Gene Information

Gene symbol: AURKB

Gene name: aurora kinase B

HGNC ID: 11390

Synonyms: Aik2, IPL1, AurB, AIM-1, ARK2, STK5, PPP1R48

Related Genes

#	Gene Symbol	Number of hits
1	CBX5	1 hits
2	INSR	1 hits
3	L1CAM	1 hits

Related Sentences

#	PMID	Sentence
1	2569023	To clarify the molecular basis of the insulin resistance, we investigated the insulin binding and kinase properties of the insulin receptor and the receptor gene in cultured skin fibroblasts of two patients (Ark-1 and Ark-2) with leprechaunism and in those of three of their parents.
2	2569023	In Ark-1, the 70% reduction in autophosphorylation correlated with the decrease in binding, whereas in Ark-2 and in the three parents included in the study, autophosphorylation of the insulin receptor was reduced below the level accounted for by a change in receptor content.
3	15846093	Addition of histone deacetylase inhibitors prior to the end of S-phase resulted in decreased HP1-beta on pericentromeric heterochromatin in S-phase and G(2), decreased pericentromeric targeting of Aurora B kinase, resulting in decreased premitotic phosphorylation of pericentromeric histone H3(S10) in G(2), followed by assembly of deficient kinetochores in M-phase.
4	16980585	Phosphorylation of H3S10 by Aurora B leads to dissociation of HP1 proteins from methylated H3K9 residues on mitotic heterochromatin.